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EPITHELIOMA ADENOIDES CYSTICUM, TRICHOEPITHELIOMA AND BASAL CELL CANCERRELATION BETWEEN THESE DISEASES, AS SHOWN BY HISTOLOGIC STUDIES OF MULTIPLE BENIGN CYSTIC EPITHELIOMA
HERBERT L. TRAENKLE, M.D.
Arch Derm Syphilol. 1940;42(5):822-839.
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A genetic relation between epithelioma adenoides cysticum (Brooke), trichoepithelioma and some examples of basal cell cancer has long been suspected. However, the concept that these conditions have a common embryonic origin has received little more than passing comment in the American literature during the past two decades. In short, effort in this field has been directed rather to the establishment of somewhat rigid clinical entities than toward an understanding of pathologic circumstances which might be common to all of them—or, at least, of which they were more or less a considerable part.
Still, certain earlier writers took the broader view of the subject. Indeed, the idea of a possible relation between epithelioma adenoides cysticum and perverted development of hair follicles is as old as the classic description of the disease. Brooke,1 in histologic sections from 2 of his cases, noted that the masses of basal cells in the corium
. . . [Full Text PDF of this Article]
Author Affiliations
BUFFALO
From the Laboratory of Dermatological Research, University of Pennsylvania.
Footnotes
Read before the Section on Dermatology at the Ninety-First Annual Session of the American Medical Association, New York, June 14, 1940.
This work was made possible by the fact that the following physicians loaned me histologic material: In the cases in group I were those of 7 members of one family, which Dr. Hyman Goldman is reporting in another paper; other contributors were Drs. John V. Ambler, Denver; Carey C. Barett, Lexington, Ky.; Samuel Feldman, New York; William H. Guy, Pittsburgh; L. W. Ketron, Baltimore; C. F. Lehman, San Antonio, Texas; A. J. Markley, Denver; Hamilton Montgomery, Rochester, Minn.; O. S. Philpott, Denver; Raymond V. Quinlan, Meriden, Conn.; Braulio Saenz, Habana, Cuba; A. W. Stillians, Chicago; Richard L. Sutton Jr., Kansas City, Mo., and L. H. Winer, Minneapolis.
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