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  Vol. 43 No. 1, January 1941 TABLE OF CONTENTS
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LIPOID PROTEINOSIS

REPORT OF A CASE

UDO J. WILE, M.D.; JAMES S. SNOW, M.D.

Arch Derm Syphilol. 1941;43(1):134-144.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Siebenmann1 in 1908 described a rare clinical syndrome characterized by peculiar yellowish white plaques in the oral mucous membrane and associated with hypertrophic lesions of the skin. His histologic studies indicated that these plaques consisted chiefly of infiltrated hyaline material. Wiethe2 in 1924 described a similar congenital condition, which he also considered to be due to a diffuse hyaline change. Urbach3 was the first to report that the infiltrate in this unusual condition contained lipoid and that this lipoid material was of the phosphatide (lecithin) type. He suggested that the condition was essentially a metabolic disturbance, possibly due to diabetes, and gave it the name "lipoidosis cutis et mucosae." Urbach and Wiethe4 collaborated in 1929 and reported 9 cases of this syndrome occurring in four families.

In 1932 Urbach5 described clinical, histologic and biochemical observations on a total of 14 cases. He pointed out that . . . [Full Text PDF of this Article]


Author Affiliations

ANN ARBOR, MICH.; BIRMINGHAM, ALA.


Footnotes

Funds for the study of this case were made available by a grant from the Horace Rackham School of Graduate Studies.

Studies and contributions from the Department of Dermatology and Syphilology of the University of Michigan Medical School, service of Dr. Udo J. Wile.



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