
A COMPARATIVE STUDY OF SEROLOGIC TESTS FOR SYPHILIS
LESTER HOLLANDER, M.D.;
CHARLES L. SCHMITT, M.D.;
CLARA R. SCHLESINGER, B.A.
Arch Derm Syphilol. 1941;43(2):311-316.
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Since the fall of 1934 we have been particularly concerned with the evaluation of various serologic tests for syphilis. In three previous reports1 we presented some of our findings. Each report dealt with the results obtained in 3,000 consecutive patients, and in each report the Wassermann tests (with the acetone-insoluble lipoid antigen and with the cholesterolized antigen), the Kahn test (precipitation) and the Hinton test (flocculation) were compared as to sensitivity and reliability.
Interpretation of these studies indicated that in a careful serologic survey no single serologic test can be accepted as critical, that such a serologic survey should include at least four of the available procedures and, further, that obtaining a careful clinical history and a meticulous physical examination are just as important today as they were before laboratory help was as readily available.
MATERIAL
Our present report deals with the evaluation of the same four serologic tests
. . . [Full Text PDF of this Article]
Author Affiliations
PITTSBURGH
From the Pittsburgh Skin and Cancer Foundation.
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