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THE ADEQUATE DIAGNOSIS OF INFANTILE CONGENITAL SYPHILIS
NORMAN R. INGRAHAM, Jr., M.D.;
BERTRAM SHAFFER, M.D.;
BARBARA E. SPENCE, R.N.;
JAMES H. GORDON, M.D.
Arch Derm Syphilol. 1941;43(2):323-340.
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Recently the opportunity has been afforded to review in considerable detail the results obtained in a study1 completed about five years ago in which was described a clinical method of approach to the often difficult problem of diagnosing congenital syphilis in the first few weeks of postnatal life. The restudy of this material seemed especially pertinent and essential in the light of the recent applications of advancing knowledge of the quantitative estimation of syphilis reagin in the infant's blood stream (Faber and Black,2 Christie3 and Davies4) and of the effect of infantile diseases or malnutritional states other than syphilis (Caffey,5 Aries6 and Evans7) and of antisyphilitic therapy administered to the mother prepartally (Caffey,8 Christie9 and Whitridge10) on the interpretation of the roentgenogram of the infant's long bones during the neonatal period. At the time of the original study the possibility
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
From the Prenatal Syphilis Clinic, Philadelphia General Hospital; the Department of Dermatology and Syphilology, University of Pennsylvania School of Medicine, and the University of Pennsylvania Institute for the Control of Syphilis, with the cooperation of the Pennsylvania State Department of Health.
Footnotes
Assisted by a grant from the United States Public Health Service.
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