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PAUL GROSS, M.D.

Arch Derm Syphilol. 1941;43(3):504-531.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This paper deals with cutaneous eruptions not quite conforming with any well known dermatologic entity. The main feature common to all these conditions was their response to parenteral liver therapy, which suggested that they were due to a deficiency of the vitamin B complex. In none of the cases observed was a diagnosis of pellagra permitted, since the cutaneous manifestations were not typical of this disease, nor were they associated with lesions of the mucous membranes of the mouth, gastrointestinal disturbances or mental symptoms. Therefore, this classification as nonpellagrous eruptions due to deficiency of the vitamin B complex seemed justified.

In recent years chemical investigations of the vitamin B complex, studies on intracellular enzymes and their relations to vitamins and observations on experimental deficiencies in animals have thrown much light on the deficiency diseases observed in man. Although the field is large and the literature inexhaustible, it seems necessary to . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Dermatology of the Vanderbilt Clinic and the Columbia University College of Physicians and Surgeons.

Footnotes
This work was supported in part by a grant from the John and Mary R. Markle Foundation.

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