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W. VAN WINKLE, Jr., M.D.; P. J. HANZLIK, M.D.

Arch Derm Syphilol. 1942;45(3):478-481.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The successful oral use of sobisminol mass (N. N. R.) in antisyphilitic treatment has stimulated the development of closely related bismuth complexes as possible substitutes. Such complexes might shed light on the relation between the chemical nature and the gastrointestinal absorption and actions of bismuth. This report presents results of a study on the gastrointestinal absorption and toxicity of a new bismuth compound prepared from the same ingredients which enter into the composition of sobisminol mass¹ and sobisminol solution (N. N. R.). Both sobisminol mass and sobisminol solution are absorbed from the alimentary canal, and, as far as known, both contain the same active bismuth complex chemically.

The new compound was prepared by Dr. William T. Miller during his tenure of a Lilly fellowship in the Stanford University department of chemistry. Dr. Miller's original objective was to determine the chemical nature of sobisminol mass, but he could not isolate . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Department of Pharmacology, Stanford University School of Medicine.

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