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C. D. STEWART, M.D.; MILTON GOLDMAN, M.D.; MAXIMILIAN E. OBERMAYER, M.D.

Arch Derm Syphilol. 1942;45(5):933-940.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Ichthammol is a sulfonated bitumen of complex structure. As early as 1883 Baumann and Schotten,¹ after purely chemical research, drew up an empiric formula for a sulfone compound, ammonium ichthosulfonate, which they called ichthyol (sulfonated bitumen N. F. V; ichthammol N. F. VI). Three years later Unna² published the first comprehensive study on its clinical application. He recommended the compound primarily for the therapy of dermatoses, but he also mentioned that it was useful when administered internally for treating gout and rheumatic conditions. It was first used in gynecologic practice by Freund³ in 1890. Shortly thereafter Neisser⁴ and Jadassohn⁵ recommended it for the treatment of gonorrhea. More recently Scheibler⁶ and Scheibler and Rettig⁷ showed that its therapeutic effect is due to its sulfur-containing compounds, principally thiophene homologues. In 1931 Pincussen⁸ stated that one action of the substance is to effect a change . . . [Full Text PDF of this Article]

Author Affiliations
CORPUS CHRISTI, TEXAS; LOS ANGELES

From the Section of Dermatology, University of Chicago, the School of Medicine.

Footnotes
This study was supported by a grant from Merck & Co., Inc.

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