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MAJOR ANDREW G. FRANKS

Arch Derm Syphilol. 1943;47(1):97-101.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the original reports of acanthosis nigricans by Pollitzer¹ and Janovsky,² about 300 authentic cases have been described. These included instances both of the juvenile and of the malignant type of the disease. In reviewing the literature, it was noted that in the majority of the cases the disease was associated with a malignant growth in the abdomen.

The consensus is that in many cases acanthosis nigricans is due to the presence of tumors adjacent to the abdominal sympathetic system and adrenal glands. Wieder³ concluded that in many cases, including cases of the juvenile type, the disease cannot be accounted for by this hypothesis. Many investigators have described cases of acanthosis nigricans associated with some systemic maligant growth, usually involving the stomach or uterus. Many of the patients have been infants and children. Usually the younger the patient the more unlikely the association of a malignant growth. . . . [Full Text PDF of this Article]

Author Affiliations
MEDICAL CORPS, ARMY OF THE UNITED STATES

From Lawson General Hospital, Brig. Gen. W. L. Sheep commanding and Col. E. E. Cooley chief of medical service.

Footnotes
Released for publication by the War Department Manuscript Board, which assumes no responsibility, other than censorship, for the contents of the article.

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