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REPORT OF A CASE, WITH EXPERIMENTAL STUDY

ZACHARY FELSHER, M.D.

Arch Derm Syphilol. 1944;49(6):410-414.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Charles Darwin, in his work "The Variations of Animals and Plants Under Domestication,"¹ mentioned a communication from Wedderburn, wherein he described 10 men of a Hindoo family with little hair on the body, early baldness, partial anodontia and excessive dryness of the skin in hot weather. He observed that this anomalous condition did not occur in the female members of the family but was transmitted to males by healthy female conductors. Wedderburn reported this case in 1838. In 1848 Thurman² described 2 similar cases, and in 1883 Guilford³ reported another.

The total number of cases of hereditary ectodermal dysplasia known is difficult to estimate. Lord and Wolfe⁴ (1938) collected about 40 cases from the literature. De Silva⁵ (1939) mentioned 48 cases, excluding the Hindoo cases of Wedderburn (10) and the cases reported by Thadani⁶ (2) in 1921. Clouston⁷ (1939) dif . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Section of Dermatology and Syphilology, Department of Medicine, University of Chicago.

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