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DETERMINATION OF MACROCYTIC ANEMIA AS AN AID IN DIAGNOSIS OF CERTAIN DEFICIENCY DERMATOSES
GAROLD V. STRYKER, M.D.;
WILLIAM A. HALBEISEN, M.D.
Arch Derm Syphilol. 1945;51(2):116-123.
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In man, nutritional deficiencies of the various fractions of the B complex except thiamine are usually multiple; one or two symptoms are frequently present long before a fully developed disease syndrome makes its appearance. Examples of this limited effect are seen in cheilosis, greasy desquamation of the nasolabial folds, vascularization of the cornea which occurs in ariboflavinosis,1 stomatitis, gastritis, dermatitis, diarrhea and constipation which often occur singly in niacin deficiency2 and the nonpellagrous dermatoses such as those reported by Gross.3
In the experimental animal, changes involving the various tissues may be produced at will by withholding one or more of the various fractions of the B complex. These changes may be produced in the gastrointestinal tract, the nervous system, the hemopoietic system and the skin.
There are only two fractions of the B complex, niacin and riboflavin, which are known to affect cutaneous
. . . [Full Text PDF of this Article]
Author Affiliations
With the Technical Assistance of Lucille Leventhal ST. LOUIS
From the Service of Garold V. Stryker, M.D., Chair man of the Department of Dermatology, St. Louis University School of Medicine.
Footnotes
Read before the Section on Dermatology and Syphilology at the Ninety-Fourth Annual Session of the American Medical Association, Chicago, June 14, 1944.
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