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ARTHUR B. HYMAN, M.D.

Arch Derm Syphilol. 1946;53(1):26-30.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

For many years the most valuable drugs in the treatment of lupus erythematosus¹ have been gold and bismuth preparations. In cases of obstinate lupus erythematosus which does not respond to these conventional drugs and against which sundry methods have been used without success, any remedy which might improve the eruption, if only partially, is valuable. This is particularly true if the remedy is a comparatively nontoxic drug.

The organic arsenicals have long had a useful place in the treatment of lupus erythematosus. Neoarsphenamine, the silver arsphenamines, acetarsone and bismarsen have been used, with some favorable results reported for each. These facts made it seem worth while to test oxophenarsine hydrochloride, the arsenical having the best therapeutic index for syphilis, in the therapy of resistant lupus erythematosus.

In July 1942, Dr. M. B. Sulzberger first employed oxophenarsine hydrochloride in a case² of widespread chronic discoid lupus erythema . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Skin and Cancer Unit, New York Post-Graduate Medical School and Hospital, Columbia University.

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