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Keratoplastic Chemicals Become Keratolytic When Prescribed in Fatty Vehicles of High Water Content

HERMAN GOODMAN, M.D.

Arch Derm Syphilol. 1946;54(1):62-63.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The introduction of high water content vehicles for active ingredients intended for application to the skin in health and in disease requires a revision of ideas as to prescription writing. In former days, salicylic acid, for example, was prescribed in a fat and a fatlike vehicle of hydrous wool fat, petrolatum, theobroma oil, lard, prepared suet or goose grease. These were solid bases. The powdered salicylic acid was dispersed through the art of pharmacy. If the salicylic acid particles were considered as black pawns, an ointment of 10 per cent salicylic acid could be considered as 1 black pawn set among 9 white ones, representing the fat and fatlike ingredients of the vehicle. If the covered skin were then the checkerboard, 1 square in 10 would have salicylic acid; 9 squares in 10 would be covered by grease.

Today, the prescribing physician tends to write for trade name vehicles. . . . [Full Text PDF of this Article]

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NEW YORK

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