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The Source of the Antigen

SIDNEY FRIEDLAENDER, M.D.; ROBERT M. WATROUS, M.D.; SAMUEL M. FEINBERG, M.D.

Arch Derm Syphilol. 1946;54(5):517-523.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ALLERGY to penicillin has been the subject of many recent reports. Various types of reactions are recorded which may be classified under the heading of hypersensitivity. The most common allergic response described is urticaria.¹ In most instances this resembles a serum sickness type of reaction and does not interfere with the continuation of treatment. In a few cases, more severe reactions have necessitated prompt cessation of therapy. Another type of reaction is a vesicular or bullous eruption occurring shortly after the onset of treatment, which appears to be in some manner related to a previous fungous infection of the skin.² Contact dermatitis is a third manifestation frequently attributed to penicillin.³ In addition to these three types of allergy, which comprise the majority of the reactions reported, a tuberculin type of response following a single intradermal injection,⁴ and reactions of the Arthus type . . . [Full Text PDF of this Article]

Author Affiliations
DETROIT; CHICAGO

From the Division of Allergy, Department of Medicine, Northwestern University School of Medicine, and the Plant Physician's Department of Abbott Laboratories.

Footnotes
The materials used in this study were supplied by the Abbott Laboratories, North Chicago, Ill.

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