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Report of Three Cases

ROBERT L. BARTON, M.D.; ROBERT M. CRAIG, M.D.; GEORGE X. SCHWEMLEIN, M.D.; THEODORE J. BAUER, M.D.

Arch Derm Syphilol. 1947;56(1):1-6.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

EVER since 1905, when Donovan¹ described the peculiar intracellular and extracellular encapsulated organisms which he found in fresh spreads taken from ulcerative lesions of granuloma inguinale, the nature of the Donovan body has excited great interest. Though Donovan himself expressed the opinion that the organism is a protozoan, its position in the field of toxonomy was a moot point, eliciting much labor but little light, until Anderson, DeMonbreun and Goodpasture² successfully cultivated the Donovan body in the yolk of chick embryos. According to these investigators the organism is a bacillus, for which they proposed the generic name "Donovania" and the specific name "granulomatis."

The therapy of the disease was ineffective until 1913, when intravenous administration of antimony and potassium tartrate was introduced by de Beaurepaire, Aragão and Vianna.³ This drug was enthusiastically acclaimed by Low and Newham,⁴ Pardo,⁵ and Randall, Small and Belk.⁶

Fraser . . . [Full Text PDF of this Article]

Author Affiliations
DUBUQUE, IOWA; Senior Assistant Surgeon, United States Public Health Service; Senior Assistant Surgeon (R), United States Public Health Service; Senior Surgeon, United States Public Health Service CHICAGO

From the Chicago Intensive Treatment Center, Venereal Disease Control Program, Chicago Board of Health in cooperation with the United States Public Health Service.

Footnotes
Under the direction of Herman N. Bundesen, Senior Surgeon (R) U.S.P.H.S. (Inactive), President, Chicago Board of Health.

Dr. Andrew C. Ivy, Professor of Physiology, Northwestern University, assisted and advised in the preparation of this study.

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