This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Report of Fourteen Cases in One Family in Four Generations, with a Review of the Literature

MEYER L. NIEDELMAN, M.D.

Arch Derm Syphilol. 1947;56(1):48-63.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IN A RECENT study of a wartlike eruption of the hands and feet in a boy of 17 years, investigation revealed a familial incidence of the disease involving no less than 14 members of the family in four generations. Careful histologic examination of the lesions seemed to warrant a diagnosis of Hopf's acrokeratosis verruciformis.

REPORT OF CASES

History.—

P.P.D., a 17 year old boy of Italian parentage, consulted me for warts on his hands (fig. 1), which, according to the boy's mother, had made their appearance when he was 9 months of age. He also presented acne vulgaris of the face. The mother and his 2 sisters suffered from similar lesions (figs. 2 and 3), and still further investigation led to the discovery of no less than 14 members of this family afflicted in the same manner over four generations. The genetic history is shown in figure 4. In all . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?