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A Microscopically Controlled Method of Excision

FREDERIC E. MOHS, M.D.

Arch Derm Syphilol. 1947;56(2):143-156.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE DEVELOPMENT of the chemosurgical method has been described,¹ as has the use of the method in the treatment of cancer in specific sites such as lip,² nose,³ ear⁴ and eyelid.⁵ This article concerns the chemosurgical treatment of cancer of the face, exclusive of the nose, ear, eyelid and vermilion portion of the lips.

TECHNIC

The most important feature of the chemosurgical treatment of cancer is the microscopic control of excision afforded by the technic hereinafter described.

As the term "chemosurgery" suggests, the tissues are chemically treated and then surgically excised. The chemical treatment serves to produce fixation of the tissues, so that specimens may be excised for systematic microscopic examination.

To illustrate the technic there will be described the chemosurgical treatment of a simple squamous cell epithelioma of the temple (fig. 1A).

The following steps were taken: 1. Dichloroacetic acid was applied to . . . [Full Text PDF of this Article]

Author Affiliations
MADISON, WIS.

From the Department of Surgery, Dr. E. R. Schmidt, chief, Wisconsin General Hospital, and the McArdle Memorial Laboratory for Cancer Research, University of Wisconsin School of Medicine.

Footnotes
This paper is part of a guest lecture at the Cleveland Meeting of the American Academy of Dermatology and Syphilology on Dec. 11, 1946.

This project was aided by the Thomas E. Brittingham Fund, the Wisconsin Alumni Research Foundation and the Jonathan Bowman Memorial Fund.

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