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HERMAN N. BUNDESEN, M.D.; LEO LOEWE, M.D.; ROBERT M. CRAIG, M.D.; GEORGE X. SCHWEMLEIN, M.D.; ROBERT L. BARTON, M.D.; THEODORE J. BAUER, M.D.

Arch Derm Syphilol. 1947;56(3):339-343.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WHEN Ehrlich introduced arsphenamine (N. N. R.) in 1909 it was his sincere hope that syphilis could be cured with a single injection of the drug. It soon became apparent that one injection was woefully inadequate and, moreover, that three, six or even more injections failed to yield the desired result. With the introduction of bismuth as a powerful ally, the campaign against syphilis moved closer to its goal.

Two decades after Ehrlich's discovery, following the admirable work of the Clinical Cooperative Group,¹ it was generally recognized that the use of alternating courses of the arsenicals and bismuth preparations, given continuously over a period of approximately twelve to eighteen months, in a large percentage of cases, gave the result which Ehrlich had sought in vain.

In the early 1930's, a group of physicians² once again envisioned the possibility of eradicating syphilis in a short time by utilizing an . . . [Full Text PDF of this Article]

Author Affiliations
Senior Surgeon (R), United States Public Health Service (Inactive); President, Chicago Board of Health CHICAGO; BROOKLYN; Senior Assistant Surgeon (R), United States Public Health Service DAYTON, OHIO; Senior Assistant Surgeon (R), United States Public Health Service CINCINNATI; Senior Assistant Surgeon (R), United States Public Health Service DUBUQUE, IOWA; Senior Surgeon, United States Public Health Service CHICAGO

From the office of the President of the Chicago Board of Health and the Chicago Intensive Treatment Center, Venereal Disease Control Program, in cooperation with the United States Public Health Service.

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