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Its Prevention by Use of Penicillin in Treatment of Pregnant Women with Early Infectious Syphilis

HANS C. S. ARON, M.D.; ROBERT L. BARTON, M.D.; THEODORE J. BAUER, M.D.

Arch Derm Syphilol. 1947;56(3):349-356.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

TWO REPORTS have been published recently,¹ showing spectacularly favorable results in the prevention of prenatal syphilis with the use of penicillin in the treatment of syphilitic pregnant women. It is well known that mothers with syphilis which is beyond the infectious state may deliver normal nonsyphilitic children in a varying but large percentage of cases. Transmission of syphilis to the fetus occurs much more frequently when pregnant women have syphilis in the early infectious stages than in the later stages of the disease. The efficacy of any therapeutic procedure in preventing prenatal syphilis, therefore, will be evaluated most reliably by the effect on the offspring of mothers who during pregnancy had indisputable early infectious syphilis.

When rigidly selected, the number of patients whom we saw who had proved infectious syphilis during pregnancy was limited. To obtain a satisfactory number of cases for evaluation it is necessary to compile the . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

Dr. Bauer is Senior Surgeon in the United States Public Health Service and Venereal Disease Control Officer in Chicago.; From the Chicago Intensive Treatment Center, Venereal Disease Control Program, Chicago Board of Health in cooperation with the United States Public Health Service.

Footnotes
Under the direction of Herman N. Bundesen, Senior Surgeon (R), United States Public Health Service (Inactive), President, Chicago Board of Health.

The work described in this paper was done under a contract, recommended by the Committee on Medical Research, between the office of Scientific Research and Development and the Chicago Intensive Treatment Center.

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