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Benign and Malignant Reticulum Cell Dysplasia

L. H. WINER, M.D.

Arch Derm Syphilol. 1947;56(4):480-498.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

MYCOSIS fungoides has always been a subject for debate. Many investigators consider it neither a clinical nor a histologic entity. Therefore, they have placed it in the inclusive group of lymphoblastomas. Further support for this is the fact that mycosis fungoides may simulate other diseases of this group.

The histologic structure in the clinical picture of mycosis fungoides may be granulomatous, reticuloendotheliomatous or reticulosarcomatous. The reticulum of the skin is considered by many to be the site of origin. Some have thought that the perithelium, endothelium, adventitial or periadventitial histiocytes of the blood vessels in the cutis or the fixed connective tissue cells and fibroblasts were the matrix. The widespread character of the reticulum accounts for the generalized reaction, which is a constant feature of the disease.

The variable histologic appearance of mycosis fungoides is based on the many potentialities of differentiation of the reticulum cell. Scott and Robb-Smith,¹ . . . [Full Text PDF of this Article]

Author Affiliations
BEVERLY HILLS, CALIF.

From the Division of Dermatology, University of Minnesota, and the Division of Dermatology, Minneapolis General Hospital.

Footnotes
Read at the Sixty-Sixth Annual Meeting of the American Dermatological Association, Inc., Hot Springs, Va., June 10, 1946.

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