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DEVELOPMENT OF SQUAMOUS CELL EPITHELIOMA IN EPIDERMOLYSIS BULLOSAReport of a Case
LAWRENCE K. HALPERN, M.D.
Arch Derm Syphilol. 1947;56(4):517-522.
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EPITHELIOMA has been known to occur in the lesions of such chronic cutaneous diseases as psoriasis, eczema, hypertrophic lichen planus and blastomycosis. The resulting tumor may be either basal or squamous cell epithelioma.
It is also well known that epithelioma may develop in scar tissue resulting from such causes as burns of varied origin, trauma, syphilis, tuberculosis, lupus vulgaris and lupus erythematosus. When scar tissue undergoes carcinomatous change it is generally of the squamous cell type. Obviously then, there is nothing startling in reporting the development of carcinomatous change in a lesion of chronic dermatosis or in cicatricial tissue. However, the case to be reported would appear to be of interest for two reasons. First, a search of the literature did not disclose a report of the occurrence of epithelioma as a sequel of epidermolysis bullosa, and, second, the development of bilateral squamous cell epithelioma of the lower extremities is
. . . [Full Text PDF of this Article]
Author Affiliations
ST. LOUIS
Footnotes
Studies, observations and reports from the Dermatologic Department of the Barnard Free Skin and Cancer Hospital and the Washington University School of Medicine (service of Dr. M. F. Engman Sr.).
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