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With Special Reference to Volatile Ingredients

JOHN M. SIEGEL, M.D.; LEONARD MELTZER, M.D.

Arch Derm Syphilol. 1948;57(4):660-663.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WHILE the "prophetic patch test," as published by Schwartz and Peck,¹ has come into frequent use in determining the sensitizing potency of materials and chemicals coming in contact with the skin, unless it is carried out properly erroneous conclusions may be reached. It seems to us that this point is not sufficiently stressed, as is exemplified in a recent article by Underwood and his associates.² Schwartz and Peck,³ in their "Cosmetics and Dermatitis," repeatedly stressed the fact that usage tests are often necessary in order to check and interpret the reactions obtained in patch tests, especially when dealing with certain types of chemical substances and compounds.

While patch tests give a fairly accurate idea of the relative cutaneous irritating and sensitizing properties of a new formula placed on the market, they do not always give an accurate idea of what may happen under conditions of actual use. . . . [Full Text PDF of this Article]

Author Affiliations
ALLENTOWN, PA.; NEW YORK

From the Department of Dermatology and Syphilology, New York University College of Medicine, and the Third Medical Division, Bellevue Hospital, service of Dr. F. C. Combes.

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