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SPOT TEST FOR SYPHILISUsing the Modified Meinicke Antigen of Ford Robertson and Colquhoun
R. F. LANE, F.I.M.L.T.
Arch Derm Syphilol. 1948;57(5):802-809.
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THE MEINICKE Klaerung (clarification) test for syphilis is better known in the hospitals for mental diseases than in the general hospitals in England. Geographically, it is better known and more widely used on the European continent than in North and South America, where the precipitation tests of the Kahn type and their numerous modifications have received greater attention.
For some time after its inception, the Meinicke test was treated with suspicion, on the grounds of nonspecificity. It was claimed that reaction took place with some tropical diseases, notably malaria, and with some febrile conditions, especially tuberculosis. But the Wassermann test is not entirely specific, and positive results are sometimes elicited in the absence of syphilis in such conditions as pregnancy, malaria and infectious mononucleosis, while common experience shows that 1 to 2 per cent of serums give a positive Wassermann reaction (although perhaps only weakly), which may be due to
. . . [Full Text PDF of this Article]
Author Affiliations
SHENLEY, HERTS, ENGLAND
From the Pathological Laboratory, Shenley Hospital, Shenley, Herts, England.
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