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HISTOPATHOLOGY OF ATOPIC DERMATITIS AND CHARACTERISTIC ATOPIC REACTION TO PATCH TEST
FRANK A. SIMON, M.D.;
A. J. MILLER, M.D.
Arch Derm Syphilol. 1948;58(6):728-734.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THE CHARACTERISTIC atopic reaction to patch tests with human dander and the naturally occurring lesions of the disease atopic dermatitis resemble each other grossly in the occurrence of papules, papulovesicles, redness and slight desquamation and in their chronologic development and retrogression. The natural lesions, of course, are frequently modified by trauma and sometimes by secondary infection.
Since the allergen of human dander has been found to be present not only in the scalp but also in the skin of the general body surface,1 it must be given consideration as a possible clinically important allergenic excitant of the disease. Hence it is desirable to study further, by histologic methods, the similarities and dissimilarities of the natural lesions and the reactions to patch tests.
PRESENT INVESTIGATIONS
Method and Material.—
This study is based on biopsies made of 14 specimens obtained from 9 patients with atopic dermatitis, aged 6 and 14 months and
. . . [Full Text PDF of this Article]
Author Affiliations
LOUISVILLE, KY.
From the Departments of Medicine, Bacteriology and Immunology and Pathology of the University of Louisville School of Medicine.
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