This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Report of a Case in Which an Infiltrate of Polymorphonuclear Leukocytes Represented the Earliest Lesion

WALTER F. LEVER, M.D.

Arch Derm Syphilol. 1949;59(1):31-35.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

UP TO THE time of this report, 33 cases of relapsing febrile nodular nonsuppurative panniculitis have been reported.¹ All authors agree that the definitive histologic lesion consists of a granulomatous infiltrate in which foamy macrophages predominate. Little agreement exists, however, about the initial histologic change. Ungar¹ recently described the earliest lesion as an infiltrate composed of polymorphonuclear leukocytes. The present case supports his evidence.

REPORT OF CASE

History.—

A 33 year old white man first noted, early in March 1945, a red, tender, subcutaneous nodule in the left inguinal region. Two weeks later two similar nodules developed on the buttocks. By the end of the month all three lesions had disappeared.

From July 1945 to June 1946 the patient had six similar episodes, each characterized by fever (temperature as high as 104 F.) and by the development of red, tender, subcutaneous nodules. The nodules varied in number from . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Departments of Dermatology and Pathology, Massachusetts General Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?