This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (10)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Preliminary Report on a Possible Steroid Hormonal Etiologic Relationship

FREDERICK REISS, M.D.

Arch Derm Syphilol. 1949;59(1):78-85.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DESPITE numerous investigations, psoriasis still remains not only an etiologic puzzle but a therapeutic problem. The many failures to correct associated metabolic disturbances, revealed by biochemical observations, is a clear indication that the disease is not caused primarily by hemic changes, but is rather a result of hitherto unrecognized factors. Its frequent occurrence in Central and South China also eliminates the so often mentioned dietetic, racial and climatic preferences of the disease.

Among the many hypotheses which have been proposed to clarify the causation of psoriasis, hypofunction of the adrenal glands has been favored by many investigators (Grüneberg,¹ Riehl² and Kissmeyer, Chrom and Jacobson³). This assumption is based not only on the favorable response to adrenal cortical therapy but also on the observation that psoriasis is accompanied with a vitamin C depletion (Reiss⁴ and Mage⁵) and responds favorably to its administration. Hypercholesteremia, generally associated with . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Dermatology and Syphilology, New York University College of Medicine, the Third Medical (New York University) Division, Bellevue Hospital, Service of Dr. Frank C. Combes, and the Dermatological Service of Montefiore Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?