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Analysis of One Hundred and Fifty-Three Cases

JOHN E. RAUSCHKOLB, M.D.; HAROLD N. COLE, M.D.; Burt Held, M.D.; Milton H. Gustafson, M.D.; Jack H. Bowen, M.D.; Manly Utterback, M.D.

Arch Derm Syphilol. 1949;60(5 PART I):676-689.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AFTER the original report, in 1943, by Mahoney, Arnold and Harris,¹ on the treatment of syphilis with penicillin, it soon became apparent that the necessity of administering penicillin solution at frequent intervals often presented difficult problems in treatment. In 1944 Romansky and Rittman² described a method of preparing a suspension of penicillin calcium in a mixture of white wax U. S. P. and peanut oil (penicillin injection in oil and wax U. S. P.). Intramuscular administration of this penicillin, peanut oil and white wax suspension at twenty-four hour intervals gave results as satisfactory as those obtained with multiple injections of penicillin in aqueous solution.

From Feb. 7 to Oct. 19, 1946, 160 patients with primary and secondary syphilis, and 15 patients with early latent syphilis, a total series of 175, were treated by us with penicillin injection in oil and wax. All these patients were . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

From the Department of Dermatology and Syphilology, Western Reserve University, and the Cleveland City Hospital, H. N. Cole, M.D., director.

Footnotes
Read at the Sixty-Seventh Annual Meeting of the American Dermatological Association, Inc., Murray Bay, Quebec, Canada, June 2, 1947.

The work described in this paper was done under a contract recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the Western Reserve University, and under a grant-in-aid from the National Institute of Health, United States Public Health Service.

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