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Report of a Case Controlled by Diphenhydramine (Benadryl®) Hydrochloride

HARRY W. WOOLHANDLER, M.D.

Arch Derm Syphilol. 1949;60(5 PART I):795-797.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Summer prurigo is at best an incompletely understood entity. While it is generally accepted that hypersensitivity to sunlight produces the eruption, the exact wavelength responsible has never been definitely established. Experimental reproduction of this dermatosis has been accomplished with ultraviolet rays, ordinary sunlight, sunlight passed through window glass, yellow and red rays of longer wavelength only and even alpha and gamma rays.¹ Attempts at desensitization have generally been unsuccessful, and, except for symptomatic treatment and avoidance of sunlight, no therapeutic measure of merit has been described. Thus, the dramatic response to diphenhydramine hydrochloride (benadryl hydrochloride®) in a recently treated patient appears worthy of reporting.

REPORT OF CASE

A 5 year old white girl was first seen by me on April 9, 1947, with an eruption of the cheeks and nose of four days' duration. History obtained from the mother indicated that the patient had previously had a . . . [Full Text PDF of this Article]

Author Affiliations
PITTSBURGH

From the Section of Dermatology, University of Pittsburgh School of Medicine.

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