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Possiible Clue to Etiology

CHARLES C. DENNIE, M.D.; FRANCIS P. COOMBS, M.D.

Arch Derm Syphilol. 1950;61(1):121-122.

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A. H., a 58 year old married woman, was first seen by us on Nov. 4, 1947, and a diagnosis of lichen planus hypertrophicus of the anterolateral surface of the left thigh was made. Pronounced varicose veins of both legs were found. The lesions had first appeared one year previous to the patient's first visit. Leading from the area was a moderately large varicose vein, tortuously running toward the saphenous vein at the junction of the upper and the middle third of the thigh. This varix had been present for some time previous to the appearance of the lesions. Biopsy showed typical lichen planus hypertrophicus.

Microscopic observations were as follows: The keratin layer was thickened. One follicle was widened, with decided keratotic plugging. Relative and absolute hyperkeratosis, an increase in the stratum granulosum, acanthosis, slight liquefactive degeneration of the basal cell layer and mild lymphocytic infiltration in the upper portion . . . [Full Text PDF of this Article]

Author Affiliations
KANSAS CITY, MO.

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