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ROBERT R. KIERLAND, M.D.; WALLACE E. HERRELL, M.D.; PAUL A. O'LEARY, M.D.

Arch Derm Syphilol. 1950;61(2):185-195.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WHAT MIGHT be called the "antibiotic era" of syphilotherapy began with the introduction of penicillin in the treatment of syphilis. Naturally, therefore, antibiotics developed since the introduction of penicillin also have been examined for their possible value in the treatment of syphilis. The new antibiotic aureomycin appears to have a wide range of antibacterial activity. The present report is concerned with an expansion of our previously reported investigations on its oral use in the treatment of syphilis.

It was evident from the report by Heilman¹ that aureomycin possesses antispirochetal activity which is greater than that of penicillin against experimental infectious relapsing fever and leptospirosis icterohaemorrhagica. His observations led us to administer aureomycin orally to patients with early infectious syphilis² and to patients with late cutaneous syphilis and neurosyphilis³. The results obtained showed that aureomycin has definite antisyphilitic activity when administered by . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN.

From the Section on Dermatology and Syphilology (Dr. Kierland and Dr. O'Leary) and the Division of Medicine (Dr. Herrell), Mayo Clinic.

Footnotes
Supplies of aureomycin were provided by Lederle Laboratories Division, American Cyanamid Company.

Read at the Sixty-Ninth Annual Meeting of the American Dermatological Association, Inc., Hot Springs, Va., May 27, 1949.

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