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I. ZELIGMAN, M.D., D. Med. Sc.

Arch Derm Syphilol. 1950;61(5):853-854.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The usual methods of examination for porphyrins in the urine demand considerable time and effort on the part of the physician and the technician. No fast reliable method for quantitatively estimating coproporphyrin in the urine has been devised, but the significance of increased excretion of this pigment has been found to be unimportant in the dermatoses¹ though of importance and interest in the anemias, hepatopathies and febrile disorders.

Porphyria, on the other hand, in which uroporphyrin, an abnormal porphyrin, is found in the urine, may be of great significance to dermatologists. With porphyria, one may see various dermatologic symptoms. Hydroa estivale, epidermolysis bullosa-like lesions, sclerodermatous eruptions, hypertrichosis and hyperpigmentation have been recognized to occur with porphyria. In addition, persons with porphyria not infrequently have gastrointestinal or neuropsychiatric complaints.

Study of several cases of porphyria has taught me that the diagnosis may be made in any dermatologist's . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Dermatology and Chemical Divisions, Department of Medicine, Johns Hopkins Hospital and School of Medicine.

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