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JOHN R. HASERICK, M.D.

Arch Derm Syphilol. 1950;61(6):889-891.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE BLOOD of patients with acute disseminated lupus erythematosus has been found to contain a factor which can be detected by adding the whole plasma of these patients to preparations of human or dog bone marrow. This presentation is concerned with the detection of the "L. E. factor," with its disappearance during complete remissions of the disease and with its identification or association with the gamma globulin fraction of the plasma.

Study of the bone marrow was introduced as an investigative field in acute disseminated lupus erythematosus by work originally done at the special hematology laboratory of the Mayo Clinic. Richmond¹ detected a phenomenon of phagocytosis in the bone marrow of a man who was extremely ill with an undetermined disease. Characteristic of this phenomenon was the cell, which she called the "tart cell." This cell is a polymorphonuclear leukocyte which contains a small inclusion. Hargraves . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

From the Department of Dermatology, Cleveland Clinic.

Footnotes
This paper is the second in a "Symposium on Lupus Erythematosus," held at the Bronx Dermatological Society on Dec. 15, 1949.

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