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CHARLES M. PLOTZ, M.D.; J. WALLACE BLUNT, M.D.; CHARLES RAGAN, M.D.

Arch Derm Syphilol. 1950;61(6):913-918.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE Hench and his co-workers¹ described the dramatic effect of cortisone and pituitary adrenocorticotropic hormone, or ACTH, on patients with rheumatoid arthritis, interest in the effect of these substances on the "mesenchymal diseases" has mounted. Independent reports by Boland and Headley in Los Angeles,² Thorn in Boston³ and Ragan and co-workers in New York⁴ amply confirmed that there are beneficial effects observed in rheumatoid patients. Only scattered reports from Hench,¹ Thorn,³ Grace⁵ and others⁶ to the time of writing indicated beneficial results from this therapy in other members of the group of connective tissue disorders which includes rheumatic fever, scleroderma, dermatomyositis, periarteritis nodosa and disseminated lupus erythematosus.

This report deals with 3 patients with disseminated lupus, erythematosus, observed on the medical service of the Presbyterian Hospital, who were treated with ACTH. Experimental work conducted in an effort to explain . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Departments of Medicine, Surgery and Surgical Pathology, Columbia University College of Physicians and Surgeons, and the Edward Daniels Faulkner Arthritis Clinic of the Presbyterian Hospital.

Footnotes
Postdoctorate Research Fellow, National Institutes of Health, United States Public Health Service.

This paper is the eighth in a "Symposium on Lupus Erythematosus," held at the Bronx Dermatological Society on Dec. 15, 1949.

Supplies of ACTH were provided through the courtesy of Dr. John R. Mote, Medical Director, The Armour Laboratories, Chicago.

Supported in part by grants from the Masonic Foundation for Medical Research and Human Welfare and the Office of Naval Research, United States Navy.

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