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SQUAMOUS-CELL EPITHELIOMA THAT SIMULATES SARCOMA
LAURENCE J. UNDERWOOD, M.D.;
HAMILTON MONTGOMERY, M.D.;
ALBERT C. BRODERS, M.D.
AMA Arch Derm Syphilol. 1951;64(2):149-158.
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WE WISH to report on a group of 40 Mayo Clinic cases in which the pathologic diagnosis was squamous-cell epithelioma of the skin with features of sarcoma. This series does not include any cases of epithelioma on the lip in which the pathologic picture simulated sarcoma, of which we have seen several instances. In the majority of the cases the histopathologic changes simulated those of fibrosarcoma, although in a few there were observations suggestive of other types of sarcoma, hemangioendothelioma, and nonmelanotic melanoepithelioma. The clinical appear- ance of this group of neoplasms is not diagnostic per se, and frequently the lesions may present features of a granuloma rather than features of an epithelial neoplasm (Fig. 1). In addition to the 40 cases encountered at the clinic, one of us (H. M.) has seen 12 additional specimens of tissue sent in from the outside which revealed the features of squamous-cell epithelioma that
. . . [Full Text PDF of this Article]
Author Affiliations
ROCHESTER, MINN.
Footnotes
Fellow in Dermatology and Syphilology, Mayo Foundation (Dr. Underwood). From the Section on Dermatology and Syphilology (Dr. Montgomery) and the Division of Surgical Pathology (Dr. Broders), Mayo Clinic.
Abstract, with additions, of thesis submitted by Dr. Underwood to the Faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of Master of Science in Dermatology and Syphilology.
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