This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (2)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

HUGH McCULLOCH, M.D.; I. ZELIGMAN, M.D., D.Med.Sci.

AMA Arch Derm Syphilol. 1951;64(2):198-199.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Brocq¹ in 1894 introduced the term "fixed drug eruption" to denote an unusual form of eruption produced by the ingestion of antipyrine. The chief characteristic of this eruption was that it recurred in the primarily affected area each time antipyrine was taken. The manifestations were erythematous, pigmentary or vesiculobullous plaques sometimes involving the mucosal orifices. The term "fixed"² has since been extended to various types of eruptions, such as urticarial, erythematous or eczematous ones, that reappear in the parent site as a result of the use of a drug. J. Jadassohn³ extended the term "fixed" to include extracutaneous effects from drugs characterized by the recurrence of symptoms in the original sites in tissues other than the skin or mucous membranes. The case reported below is an example of a typical fixed drug eruption and an unusual extracutaneous effect, an epididymitis, due to the ingestion of antipyrine.

REPORT OF A CASE . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

Footnotes
Sponsored by the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are the result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.

Resident in Training in Dermatology and Syphilology, Veterans Administration Hospital, Fort Howard, Md. (Dr. McCulloch), and Attending Physician in Dermatology and Syphilology, Veterans Administration Hospital, Fort Howard, Md.; Instructor in Dermatology, Johns Hopkins University School of Medicine, and Assistant Dermatologist, Johns Hopkins Hospital (Dr. Zeligman).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?