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CARL M. PEARSON, M.D.; JOHN L. FROMER, M.D.

AMA Arch Derm Syphilol. 1951;64(3):362-364.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Generalized or localized pruritus is a symptom frequently encountered in medical and dermatologic practice. It is evident from the large number of therapeutic remedies which have been applied both locally and systemically in pruritus that no single means of controlling itching in the majority of these cases is available.

Within the past two years several reports¹ have appeared which have indicated that the parenteral administration of adenylic acid (adenosinemonophosphate) may be of value in the relief of pruritus from many different causes. On the basis of these results, the suggestion has been made^1b that there may be a fundamental mechanism for pruritus which involves the metabolism of adenylic acid.

Recently we have had an opportunity to observe the effect of adenylic acid and a related compound, adenosinetriphosphate, on a series of patients with pruritus originating from a variety of conditions, chiefly dermatologic. In general, the results of these . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

Footnotes
Departments of Internal Medicine and Dermatology, Lahey Clinic.

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