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LILA REDMOND McCORRISTON, M.D.

AMA Arch Derm Syphilol. 1952;65(2):224-227.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

EMULSIFYING agents administered orally are stated to improve the absorption of fat¹ and fat-soluble vitamins² from the gastrointestinal tract. Marked improvement of a secondary pellagra-like eruption was observed in a patient with idiopathic steatorrhea treated in this manner. This response suggested the possibility that faulty fat absorption may produce abnormalities in skin metabolism; the thick, dry, hyperpigmented skin in biliary cirrhosis and intestinal lipodystrophy are cases in point.³

Alterations of the composition of tissue fat have been observed in rats fed a fat-deficient diet,⁴ and small doses of the C-18 unsaturated fatty acids have caused healing of the desquamated epithelial surfaces caused by this deficiency.⁵ In patients with eczematous dermatitis the low iodine numbers of the serum fatty acids were increased by the feeding of unsaturated fatty acids, and there was concomitant improvement in the skin.⁶ In psoriatic patients the surface fat from the uninvolved skin has been reported to have a . . . [Full Text PDF of this Article]

Author Affiliations
MONTREAL, CANADA

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman) and the Skin and Cancer Unit of New York University Hospital.

Footnotes
This study was supported by a grant from the Abbott Research Laboratories.

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