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  Vol. 65 No. 2, February 1952 TABLE OF CONTENTS
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CROSSED FIXED DRUG ERUPTION FROM TWO ANTIBIOTICS

ASHTON L. WELSH, M.D.

AMA Arch Derm Syphilol. 1952;65(2):232.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

I have experienced a fixed drug eruption from aureomycin.1 Terramycin was ingested on two occasions between the periods of ingestion of aureomycin and preceding the fixed eruption produced by the latter drug. No eruption or untoward reaction of any type occurred from ingestion of terramycin on these occasions.

After the eruption appeared from aureomycin, taken for the last episode of upper respiratory infection for which it was used,1 terramycin was administered to complete treatment. The lesions of the fixed eruption from aureomycin became more marked and persisted much longer than the earlier episodes of eruption, in the same sites produced by aureomycin alone. At that time, this increase in severity and prolonged interval of the fixed drug eruption from aureomycin were not attributed to terramycin. The phenomena were interpreted as having their basis in increased sensitization to aureomycin due to repeated ingestion of this drug.

Six months later, . . . [Full Text PDF of this Article]


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