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Comparison with Neomycin and Bacitracin

HERBERT RATTNER, M.D.; H. HAROLD RODIN, M.D.

AMA Arch Derm Syphilol. 1952;65(6):656-662.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SOME TIME ago the director of the Hektoen Institute, which is the division of research of the Cook County Hospital in Chicago, enlisted our cooperation for a study of several new antibiotic agents. The Institute was interested particularly in a new type of penicillin, l-ephenamine penicillin G (penicillin 92).¹ It has an antibacterial spectrum which in vitro parallels that of penicillin G, but which differs from it in one important respect. l-Ephenamine penicillin G is thought to have hypoallergenic properties similar to those attributed to penicillin O.²

Although there are many excellent agents available for the topical treatment of pyogenic infections of the skin, each of them has certain limitations. The better ones are the broad-spectrum antibiotics, but even among these there is none that has proved to be effective in all cases. All the antibacterial drugs on occasion may produce allergic reactions, while some . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Hektoen Institute, Cook County Hospital, and the Department of Dermatology, Northwestern University Medical School.

Footnotes
Read before the Seventy-First Annual Meeting of the American Dermatological Association, Hot Springs, Va., May 23 to 26, 1951.

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