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AUREOMYCIN AND ITS EFFECT IN EARLY SYPHILISOne-Year Progress Report
JACK RODRIQUEZ, M.D.;
SEYMOUR WEINSTEIN, M.D.;
GEORGE E. PARKHURST, M.D.
AMA Arch Derm Syphilol. 1952;66(1):59-64.
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IN APRIL, 1950, in a progress report1 based on a study of 67 patients with dark-field-positive syphilis, it was concluded that oral administration of 70 gm. of aureomycin over 11 days causes a progressive decline in the serologic titer, rids syphilis lesions of surface spirochetes in an average of 39 hours, maintains high
aureomycin blood levels, and shows cerebrospinal fluid aureomycin levels for 50% of the patients.
The present study is based on the results of observation for 12 to 15 months on 101 patients with dark-field-positive secondary syphilis. All patients were previously untreated for syphilis.
The distribution of patients by race, sex, and age is indicated in the table. The age range for the group was 17 to 69 years. The median age was 24 years. Eighty-two patients were Negro; 18 were white, and 1 was Indian. Fifty-eight were men, and 43 women. The patients were
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO
From the Chicago Intensive Treatment Center, Venereal Disease Control Program, Chicago Board of Health, in cooperation with the United States Public Health Service.
Footnotes
This paper was prepared under the direction of Herman N. Bundesen, M.D., President, Chicago Board of Health.
Medical Director, Chicago Intensive Treatment Center; Research Associate, Kettering Foundation for Medical Research; Special Consultant, United States Public Health Service, Division of Venereal Disease (Dr. Rodriquez); Assistant Medical Director, Chicago Intensive Treatment Center (Dr. Weinstein); Venereal Disease Control Officer; Medical Officer in Charge, Chicago Intensive Treatment Center (Dr. Parkhurst).
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