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ANAPHYLAXIS FROM PENICILLINReport of a Case
GEORGE M. STROUD, M.D.
AMA Arch Derm Syphilol. 1952;66(4):491-493.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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THIS ARTICLE was written to indicate the successful treatment of a case of anaphylactic shock from a new drug, l-ephenamine penicillin G (compenamine1®), which had been reported by Longacre2 and Kadison and others3 to have been less allergenic than standard preparations.
REPORT OF CASE
At 11: 10 p. m., on Jan. 18, 1952, a 47-year-old physician suddenly became weak, pale, and cyanotic within a minute after a nurse injected (without preliminary aspiration) 300,000 units of l-ephenamine penicillin in aqueous suspension in his gluteal region because of asthmatic bronchitis which had developed four days previously. In about two minutes he was given 1.0 cc. of 1: 1,000 epinephrine hydrochloride solution subcutaneously. Within a matter of seconds he became comatose, but in another two or three minutes he was alert again. At this point I arrived and found a well-developed, heavy-set man lying on
. . . [Full Text PDF of this Article]
Author Affiliations
CLEVELAND
Footnotes
Senior Clinical Instructor in Dermatology and Syphilology, Western Reserve University Medical School; Assistant Dermatologist and Syphilologist, University Hospitals of Cleveland.
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