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  Vol. 66 No. 4, October 1952 TABLE OF CONTENTS
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ANAPHYLAXIS FROM PENICILLIN

Report of a Case

GEORGE M. STROUD, M.D.

AMA Arch Derm Syphilol. 1952;66(4):491-493.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THIS ARTICLE was written to indicate the successful treatment of a case of anaphylactic shock from a new drug, l-ephenamine penicillin G (compenamine1®), which had been reported by Longacre2 and Kadison and others3 to have been less allergenic than standard preparations.

REPORT OF CASE

At 11: 10 p. m., on Jan. 18, 1952, a 47-year-old physician suddenly became weak, pale, and cyanotic within a minute after a nurse injected (without preliminary aspiration) 300,000 units of l-ephenamine penicillin in aqueous suspension in his gluteal region because of asthmatic bronchitis which had developed four days previously. In about two minutes he was given 1.0 cc. of 1: 1,000 epinephrine hydrochloride solution subcutaneously. Within a matter of seconds he became comatose, but in another two or three minutes he was alert again. At this point I arrived and found a well-developed, heavy-set man lying on . . . [Full Text PDF of this Article]


Author Affiliations

CLEVELAND


Footnotes

Senior Clinical Instructor in Dermatology and Syphilology, Western Reserve University Medical School; Assistant Dermatologist and Syphilologist, University Hospitals of Cleveland.



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