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  Vol. 66 No. 6, December 1952 TABLE OF CONTENTS
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TREATMENT OF CONDYLOMA ACUMINATUM WITH PELTATINS

Preliminary Report

MAURICE SULLIVAN, M.D.; JAMES T. HEARIN, M.D.

AMA Arch Derm Syphilol. 1952;66(6):706-709.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PODOPHYLLOTOXIN1 quercetin,2 {alpha}-peltatin,3 and β-peltatin4 are crystalline compounds in podophyllin. We contended previously5 that podophyllotoxin was the component responsible for involution of condyloma acuminatum. When {alpha}- and β-peltatin became available,6 32 patients were treated (Table 1). Satisfactory results necessitate including these substances as effective agents against moist genital warts. The clinical response to the topically applied peltatins was identical with that described in detail for podophyllin and podophyllotoxin7 except that the peltatins produced negligible irritation to circumjacent normal tissue. Microscopic examination of involuting warts at 24 and 48 hours showed changes7 identical with those

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Author Affiliations

BALTIMORE

From the United States Public Health Service Hospital, Baltimore. This work was supported by a Grant-in-Aid from the American Cancer Society.


Footnotes

Read at the Seventy-Second Meeting of the American Dermatological Association, Colorado Springs, Colo., April 24, 1952.



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