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  Vol. 68 No. 5, November 1953 TABLE OF CONTENTS
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ECZEMATOUS HYPERSENSITIVITY TO COAL TAR

Report of Three Cases

CLAUDIA R. SIMON, M.D.; ROBERT BRANDT, M.D.

AMA Arch Derm Syphilol. 1953;68(5):584-586.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Allergic eczematous dermatitis due to coal tar occurs infrequently. Ross1 observed 170 tar and pitch workers over a 12-year period and reported only six such cases. Chmel2 described keratocystomatosis of the dorsum of the hand which occurred after therapeutic application of coal tar. A patch test with 5% coal tar gave a positive reaction.

The following are three case reports of hypersensitivity to coal tar which was used for therapeutic purposes. In two cases, an attempt has been made to trace the sensitivity-producing factor (allergen?) to some of the fractions of the tar, and a comparison with shale oil, a related substance, was undertaken.

REPORT OF CASES

CASE 1.—V. S., a 60-year-old white housewife, had a history of psoriasis and superimposed neurodermatitis of five years' duration. A hypersensitivity to coal tar was first suspected by Dr. Robert R. Kierland3 at the Mayo Clinic, in 1949, when an . . . [Full Text PDF of this Article]


Author Affiliations

CINCINNATI

From the Department of Dermatology and Syphilology of the College of Medicine of the University of Cincinnati, Dr. Leon Goldman, Director.



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