This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

HAROLD M. JOHNSON, M.D.

AMA Arch Derm Syphilol. 1953;68(6):699-713.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE SPLEEN has been a source for conjecture and confusion from both physiologic and pathologic standpoints. The participation of the spleen in various symptom complexes is still being debated and elucidated. About 20 years ago, Wise¹ and Keil² showed interest in the association of splenic malfunction, splenectomy, and lupus erythematosus. Within the last five years, isolated reports have appeared regarding the role of the spleen in the mysterious and often fatal syndrome, lupus erythematosus.

Several theories have been proposed regarding the relation of the spleen and bone marrow hemopoiesis. Dameshek and Estren³ postulated that the spleen normally exerts on the bone marrow an inhibitory effect which may become increased in splenomegaly. Increase of this normal function is called hypersplenism. Dameshek and Estren³ cited Morawitz and Eppinger, who suggested the word "hypersplenism" for the activity of the spleen associated with cytopenias. This activity inhibits . . . [Full Text PDF of this Article]

Author Affiliations
HONOLULU, T. H.

Footnotes
Read before the meeting of the American Dermatological Association, Lake Placid, N. Y., June 9 to 13, 1953.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?