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Survey of Eighty-Three Patients with Positive Plasma L. E. Tests

JOHN R. HASERICK, M.D.

AMA Arch Derm Syphilol. 1953;68(6):714-725.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SYSTEMIC lupus erythematosus was among the first diseases treated with cortisone and corticotropin. In many cases striking benefit has been reported.¹ The merit of prolonged use of steroid preparations in a maintenance program is now under evaluation.² Despite these apparent advances in treatment, patients still die from the disease. The imminent question is: How many live and for how long because of steroid therapy? (The term steroids will be used here to indicate cortisone, hydrocortisone acetate, and corticotropin.)

A study of the present day prognosis of systemic lupus erythematosus must include a comparison with the natural course of the disease before steroids were introduced. Superficially this would appear to be an easy task. Actually, owing to the broad nature of systemic lupus erythematosus, there are many difficulties. For example, no classification of lupus erythematosus has ever been universally accepted. The term disseminated means a scattering of skin lesions . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

From the Department of Dermatology, Cleveland Clinic (Earl W. Netherton, M.D., Chief), and the Frank E. Bunts Educational Institute.

Footnotes
Read before the Seventy-Third Annual Meeting of the American Dermatological Association, Lake Placid, New York, June 9, 1953.

This investigation was supported in part by a research grant from the National Institutes of Health, United States Public Health Service.

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