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SUBSTITUTE FOR LIQUID NITROGEN
EDWARD J. RINGROSE, M.D.
AMA Arch Derm Syphilol. 1953;68(6):730.
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Liquid nitrogen cryotherapy is an almost indispensable modality for those who have learned its virtues. However, it may not be available at any time for some and not always available for others.
An effective substitute is carbon dioxide slush. Though slower in producing freezing than liquid nitrogen, it is more rapid, more adaptable to irregular lesions, and freezes more uniformly than solid carbon dioxide. It may be quickly prepared as follows: Carbon dioxide snow, collected in the usual chamois-skin bag, is placed in a half-pint Thermos bottle (preferably of the squat, wide-mouth type, for ease in dipping with an applicator) and acetone added with stirring until a slush of the desired consistency (not too wet) is obtained. This is then applied to the appropriate lesion—seborrheic keratosis, verruca, senile keratosis, molluscum contagiosum, etc.—with a cotton-tipped applicator until a white halo develops about the lesion.
If multiple lesions are being treated it
. . . [Full Text PDF of this Article]
Author Affiliations
BERKELEY, CALIF.
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