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SAMUEL AYRES III, M.D.; SAMUEL AYRES, Jr., M.D.

AMA Arch Derm Syphilol. 1954;69(4):502-503.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a previous report by us on the use of 1% chlorcyclizine hydrochloride in a greaselesss ointment base (Perazil cream, Burroughs Wellcome & Company, Inc.) for the relief of pruritus, it was stated that at that time no cases of contact sensitization from its use had been observed by us, although the preparation had been used in several hundred cases over a period of more than a year.

It was further stated that as the use of this preparation increased, it was to be expected that a certain incidence of sensitization would become evident, but that it would be significantly lower than in the case of the other antihistaminic drugs which have been made available for topical application.

Since that report, we have used 1% chlorcyclizine hydrochloride ointment in many hundred additional patients. Its over-all effectiveness as an antipruritic and the high degree of tolerance to it have made it . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

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