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  Vol. 72 No. 2, August 1955 TABLE OF CONTENTS
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The Significance of a Positive L. E. Phenomenon

RICHARD S. WEISS, M.D.; SHELDON SWIFT, M.B., Ch.B. (Liverpool)

AMA Arch Derm. 1955;72(2):103-112.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the interesting discovery of the L. E. phenomenon by Hargraves and his co-workers,1 the diagnosis of systemic lupus erythematosus has been vastly facilitated and has been made in a number of hitherto obscure conditions. Moreover, certain cases of rheumatic and allied diseases have presented this blood picture, raising the question of whether or not this group of diseases is another manifestation of the etiologic agent which causes lupus erythematosus. Furthermore, the phenomenon has been reported in patients with drug allergies, and it has been suggested that the increase in the number of patients with lupus erythematous is due not only to more acute diagnosis and the rising interest in the disease, but also to the indiscriminate use of the sulfonamides and the antibiotics, especially penicillin.

During the past year, we have examined a fairly large series of bloods from patients whose diseases . . . [Full Text PDF of this Article]


Author Affiliations

St. Louis

From the Dermatological Division of the Department of Medicine, School of Medicine, Washington University, the Barnard Free Skin and Cancer Hospital, and the Barnes Hospital.


Footnotes

Submitted for publication April 26, 1955.

Presidential address read at the 75th Annual Meeting of the American Dermatological Association, Inc., Belleair, Fla., April 18, 1955.



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