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V. The Role of the Regional Lymph Node

ADOLPH ROSTENBERG, Jr., M.D.; WILLIAM R. BEST, M.D.

AMA Arch Derm. 1955;72(3):221-228.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THEORETICAL INTRODUCTION

It has been reasonably well shown that the regional lymph node plays an important role in the development of certain types of antibodies. The work of McMaster and Hudack¹ and of Ehrich, Harris and their colleagues² clearly indicates that antibody is made, at least in part, in the regional node, i. e., the node adjacent to the site of introduction of the antigen, and it is probably made there prior to its manufacture elsewhere.

The nature of the antibody in the delayed type of sensitization is still a matter for argument. We are assuming that practically all workers in this field would agree that the delayed types of allergic sensitization, which comprise the bacterial (tuberculin) and the eczematous (contact) varieties, are brought about by antibodies or an antibody-like material. While any remarks that we may make probably apply to both varieties of the . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

From the Department of Dermatology and the Allergy Unit (Dr. Rostenberg) and the Department of Medicine (Dr. Best), University of Illinois College of Medicine.

Footnotes
Submitted for publication May 27, 1955.

Supported by U. S. Public Health Service Grant G3424.

Read before the 75th Annual Meeting of the American Dermatological Association, Inc., Belleair, Fla., April 20, 1955.

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