Porokeratosis of Mibelli. Presented by DR. O. CANIZARES.
Patient: G. S. Sex: Male. Color: White. Age: 66.
Duration: 56 years; progressive.
History: First developed a lesion on the left thigh at the age of 10 years and has since been slowly developing new lesions. Once a lesion completely develops, it remains permanently unchanged. The lesions are all pruritic.
Location: Generalized: scrotum, penis, left thigh mesially, right axilla, scalp, hand.
Description: Each lesion is sharply demarcated and has a flat or slightly depressed center and a narrow, elevated keratotic border. The lesions in the intertriginous areas appear softer, are more moist and tend to macerate.
Biopsy: In one portion of the skin section there are changes visible in the epidermis, consisting of hyperkeratosis, slight acanthosis, and slight hypergranulosis in places. In one place there is a deep groove filled with a hyperkeratotic mass, at the lower portion of which there are
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