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Oxytetracycline Intramuscular in the Treatment of Early Syphilis
G. ROBERT BALER, M.D.
AMA Arch Derm. 1956;73(5):489-492.
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Although the incidence of syphilis has been declining, this disease has by no means been eradicated, and it always maintains the potential of rising to former heights. It is therefore imperative that we continue our interest in its therapy.
This report concerns the effectiveness of oxytetracycline* intramuscular in early syphilis. This form of the drug has not been previously investigated in syphilotherapy; it has, however, been used with good results in the treatment of the treponematosis, yaws, as reported by Loughlin and his associates.1 Both oral and intravenous forms of the wide-spectrum antibiotics have now been employed in the treatment of syphilis. However, prior to this present report chloramphenicol was the only one of this class of antibiotics that had been utilized by the intramuscular route.
Intramuscular administration of a drug has certain definite advantages. In dealing with an infectious disease such as syphilis, it
. . . [Full Text PDF of this Article]
Author Affiliations
Boston
From Davidson County Health Department, Nashville, Tenn.
Footnotes
Submitted for publication Aug. 3, 1955.
Public Health Service Research Fellow, Dermatology, Boston University School of Medicine; Formerly Venereal Disease Control Officer, U. S. Public Health Service, Nashville.
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